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"Normalcy" is an open source (licensed under Apache 2) software package developed by the Electronic Radiology Laboratory http://erl.wustl.edu/ at Washington University School of Medicine for automated processing of MR and CT data to extract morphometric parameters of the head. We developed normalcy under NIH grant R43 NS67726, Pediatric Head Models for Improved Imaging of Neurological Development. The 2 main uses of normalcy are 1) to measure tissue thickness (scalp, skull, CSF) and skull density along a specified surface normal (See Figure 1); 2) to measure braincase volume, skull circumference, and skull length, width, and height (See Figure 2). These uses are published in references [1] and [2] respectively. Normalcy also registers MR data to CT data in order to calculate the CSF values. Click the link "Normalcy" to access download site.
Figure 1.
References:
- Smith KE, Politte D, Reiker G, Nolan T, Hildebolt C, Mattson C, Tucker D, Prior F, Turovets S, Larson-Prior L. Automated Measurement of Pediatric Cranial Bone Thickness and Density from Clinical Computed Tomography. 34th Annual International IEEE EMBS Conference 2012, San Diego, CA. 978-1-4577-1787-1/12/ 2012 IEEE
- Kirk Smith K, David Politte D, Gregory Reiker G, Tracy S. Nolan T, Charles Hildebolt C, Chelsea Mattson C, Don Tucker D, Fred Prior F, Sergei Turovets and Linda J. Turovets S, Larson-Prior. Automated Measurement of Skull Circumference, Cranial Index, and Braincase Volume from Pediatric Computed Tomography. 35th Annual International , IEEE EMBS Conference 2013, Osaka, JapanConf. 2013; 3977-3980. doi: 10.1109/EMBC.2013. (In Press)6610416
Click "Normalcy" to access download site.
Figure 2.
Figure 3.
